Keratoacanthoma - Symptoms and Treatment of Keratoacanthoma
keratoacanthoma is a common skin disorder also called "KA" by dermatologists and is characterised by deep bulbous lobules of keratinizing well differentiated squamous epithelium with central keratin filled crater.
Keratocanthomas occur when cells in hair follicles grow abnormally.
The KA is considered a form of squamous-cell carcinoma by most authorities.
Keratoacanthomas begin as small pimple-like bumps on the skin. The center of the growth is crater-like and solid. However, keratoacanthomas grow very quickly, and can be over 2.5 cm (1 in.) wide within one to two months. Sunlight, chemical carcinogens, Trauma and genetic factors are the main causes of keratoacanthoma.
keratoacanthoma Treatment and Prevention
Keratoacanthomas are treated by removing the growth.
Surgery Surgical excision is recommended in that KA cannot always be distinguished from SCC on clinical findings.
Systemic retinoids, such as isotretinoin, are a consideration for patients with lesions too numerous for surgical intervention.
Another treatment that has also been effective is the use of 5-fluorouracil injections. These injections are given at the site of the skin growth. They are used for growths that are in their later stages.
Radiation therapy may be useful in selected patients with large tumors in whom resection will result in cosmetic deformity or for tumors that have recurred following attempted excisional surgery.
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